Molecule Details
InChIKeySQUNOCMDMIQIQK-OAHLLOKOSA-N
Compound Name(2R)-2-((4-(benzylamino)-8-(1-methylethyl)pyrazolo(1,5-a)(1,3,5)triazin-2-yl)amino)butan-1-ol
Canonical SMILESCC[C@H](CO)Nc1nc(NCc2ccccc2)n2ncc(C(C)C)c2n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Cross-Family
Avg pChEMBL7.21
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB08285
Drug Name(2R)-2-{[4-(benzylamino)-8-(1-methylethyl)pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino}butan-1-ol
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 27217 CHEMBL482193 ChemSpider: 24700216 PDB: NNN PubChem:25190761 PubChem:99444756
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
P24864 CCNE1 Homo sapiens Human PF02984 PF00134 7.5 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 7.4 IC50 ChEMBL;BindingDB
P20248 CCNA2 Homo sapiens Human PF02984 PF00134 PF16500 7.4 IC50 ChEMBL
O60563 CCNT1 Homo sapiens Human PF00134 PF21797 7.4 IC50 ChEMBL;BindingDB
P50750 CDK9 Homo sapiens Human PF00069 7.4 IC50 ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 7.2 IC50 ChEMBL
Q15078 CDK5R1 Homo sapiens Human PF03261 7.2 IC50 ChEMBL;BindingDB
P06493 CDK1 Homo sapiens Human PF00069 7.1 IC50 BindingDB
P50613 CDK7 Homo sapiens Human PF00069 6.8 IC50 ChEMBL
P51946 CCNH Homo sapiens Human PF16899 PF00134 6.8 IC50 ChEMBL;BindingDB
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P20248 CCNA2 Cyclin-A2 binder targets
P24941 CDK2 Cyclin-dependent kinase 2 binder targets