Molecule Details
InChIKeySQUNAWUMZGQQJD-UHFFFAOYSA-N
Canonical SMILESCCc1ccc(C(=O)C(C)CN2CCCCC2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL7.33
SourceChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB08992
Drug NameEperisone
CAS Number64840-90-0
Groups investigational
ATC Codes M03BX09
DescriptionEperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression of the pain reflex. It is not approved for use in the United States, but is available i...

Categories: Agents causing hyperkalemia Antiarrhythmic agents Autonomic Agents Bradycardia-Causing Agents Calcium Channel Blockers Calcium-Regulating Hormones and Agents Cardiovascular Agents Central Nervous System Agents Central Nervous System Depressants Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Substrates Ketones Membrane Transport Modulators Moderate Risk QTc-Prolonging Agents Muscle Relaxants Muscle Relaxants, Centrally Acting Agents Musculo-Skeletal System Neuromuscular Agents Parasympatholytics Peripheral Nervous System Agents QTc Prolonging Agents Vasodilating Agents
Cross-references: ChEBI: 77070 CHEMBL1902981 ChemSpider: 3123 D01671 PubChem:3236 PubChem:310264953 Wikipedia: Eperisone
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q99720 SIGMAR1 Homo sapiens Human PF04622 8.6 IC50 ChEMBL
P08172 CHRM2 Homo sapiens Human PF00001 6.1 Ki ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P08684 CYP3A4 Cytochrome P450 3A4 substrate enzymes