Molecule Details
| InChIKey | SQPQTOPKWPTTHU-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1,4-Dihydro-1-(2-naphthoylmethyl)-4-oxo-3-pyridinesulfonamide |
| Canonical SMILES | NS(=O)(=O)c1cn(CC(=O)c2ccc3ccccc3c2)ccc1=O |
| Clinical Status | Clinical Multi-Target |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.95 |
| Source | ChEMBL;BindingDB;TTD_MultiTarget |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P00918 | CA2 | Homo sapiens | Human | PF00194 | 7.0 | Ki | ChEMBL;BindingDB |
| P18505 | GABRB1 | Homo sapiens | Human | PF02931 PF02932 | 7.0 | pIC50 | TTD_MultiTarget |
| Q16790 | CA9 | Homo sapiens | Human | PF00194 | 6.9 | Ki | ChEMBL;BindingDB |
| O43570 | CA12 | Homo sapiens | Human | PF00194 | 6.9 | Ki | ChEMBL;BindingDB |