Molecule Details
InChIKeySPYHMOFSJGTUNP-UHFFFAOYSA-N
Compound Name4-[2-(4-fluorophenyl)imidazo[1,2-a]pyrazin-3-yl]-N-(2-methoxyethyl)pyrimidin-2-amine
Canonical SMILESCOCCNc1nccc(-c2c(-c3ccc(F)cc3)nc3cnccn23)n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL6.44
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P48730 CSNK1D Homo sapiens Human PF00069 7.8 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.7 Ki ChEMBL
P45984 MAPK9 Homo sapiens Human PF00069 6.4 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.3 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P48729 CSNK1A1 Homo sapiens Human PF00069 6.2 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.2 Ki ChEMBL
P42679 MATK Homo sapiens Human PF07714 PF00017 PF00018 6.1 Ki ChEMBL
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.0 Ki ChEMBL