Molecule Details
InChIKeySPWZXWDPAWDKQE-UHFFFAOYSA-N
Compound NameNaluzotan
Canonical SMILESCC(=O)Nc1cccc(N2CCN(CCCCNS(=O)(=O)CC3CCCCC3)CC2)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL7.15
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB05562
Drug NameNaluzotan
CAS Number740873-06-7
Groups investigational
ATC Codes nan
Descriptionnan
Categories: Agents that produce hypertension Amides Antidepressive Agents Central Nervous System Depressants Neurotransmitter Agents Serotonin 5-HT1 Receptor Agonists Serotonin Agents Serotonin Receptor Agonists Sulfones Sulfur Compounds
Cross-references: BindingDB: 50187377 CHEMBL209821 ChemSpider: 9605731 Wikipedia: Naluzotan ZINC: ZINC000003963096
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P08908 HTR1A Homo sapiens Human PF00001 8.3 Ki ChEMBL;BindingDB
Q99720 SIGMAR1 Homo sapiens Human PF04622 7.0 Ki ChEMBL;BindingDB
P34969 HTR7 Homo sapiens Human PF00001 6.2 Ki ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P08908 HTR1A 5-hydroxytryptamine receptor 1A agonist targets