Molecule Details
| InChIKey | SPEGERVLTUWZPA-UHFFFAOYSA-N |
|---|---|
| Compound Name | N~1~-({5-[4,4-bis(ethoxymethyl)cyclohexyl]-1H-pyrazol-4-yl}methyl)-N~1~,N~2~-dimethylethane-1,2-diamine |
| Canonical SMILES | CCOCC1(COCC)CCC(c2n[nH]cc2CN(C)CCNC)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.48 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O60678 | PRMT3 | Homo sapiens | Human | PF21137 PF21336 PF06325 PF22528 | 8.8 | IC50 | ChEMBL |
| Q9NR22 | PRMT8 | Homo sapiens | Human | PF06325 PF22528 | 8.7 | IC50 | ChEMBL |
| Q96LA8 | PRMT6 | Homo sapiens | Human | PF13649 PF22528 | 8.6 | IC50 | ChEMBL |
| Q99873 | PRMT1 | Homo sapiens | Human | PF13649 PF22528 | 8.5 | IC50 | ChEMBL |
| Q86X55 | CARM1 | Homo sapiens | Human | PF11531 PF06325 PF22528 | 7.8 | IC50 | ChEMBL |