Molecule Details
InChIKeySOYCFODXNRVBTI-UHFFFAOYSA-N
Compound NameA-1155463
Canonical SMILESCN(C)CC#Cc1ccc(OCCCc2sc(N3CCc4cccc(C(=O)Nc5nc6ccccc6s5)c4C3)nc2C(=O)O)c(F)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL7.25
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
Q07817 BCL2L1 Homo sapiens Human PF00452 PF02180 9.6 IC50 ChEMBL;BindingDB
Q92843 BCL2L2 Homo sapiens Human PF00452 PF02180 7.7 Ki ChEMBL;BindingDB
P10415 BCL2 Homo sapiens Human PF00452 PF02180 7.1 Ki ChEMBL;BindingDB
Q99720 SIGMAR1 Homo sapiens Human PF04622 6.9 Ki ChEMBL
P14867 GABRA1 Homo sapiens Human PF02931 PF02932 6.1 Ki ChEMBL
Q5BJF2 TMEM97 Homo sapiens Human PF05241 6.1 Ki ChEMBL