Molecule Details
InChIKeySOVYWBOZOBVFLP-UHFFFAOYSA-N
Compound Name3-[(3,4-Dimethylphenyl)methylamino]-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione
Canonical SMILESCc1ccc(CNc2c(Nc3ccncc3)c(=O)c2=O)cc1C
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Homologous
Avg pChEMBL6.43
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
P49841 GSK3B Homo sapiens Human PF00069 6.8 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.7 Ki ChEMBL
Q5VT25 CDC42BPA Homo sapiens Human PF00130 PF00780 PF08826 PF15796 PF25346 PF00069 PF00433 6.7 Ki ChEMBL
Q8NE63 HIPK4 Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q13976 PRKG1 Homo sapiens Human PF00027 PF16808 PF00069 6.6 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.3 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.3 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 6.2 Ki ChEMBL
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 6.0 Ki ChEMBL
Q9Y6M4 CSNK1G3 Homo sapiens Human PF12605 PF00069 6.0 Ki ChEMBL