4-amino-3-(3H-imidazo[4,5-b]pyridin-2-yl)-1,7-naphthyridin-2(1H)-one

InChIKey	`SNYMIRFSGCNEHH-UHFFFAOYSA-N`
Compound Name	4-amino-3-(3H-imidazo[4,5-b]pyridin-2-yl)-1,7-naphthyridin-2(1H)-one
Canonical SMILES	`Nc1c(-c2nc3ccc[nH]c-3n2)c(O)nc2cnccc12`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	8.22
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P11362	FGFR1	Homo sapiens	Human	PF07679 PF00047 PF07714	8.2	pIC50	TTD_MultiTarget
P17948	FLT1	Homo sapiens	Human	PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854	8.2	IC50	ChEMBL;BindingDB