Molecule Details
| InChIKey | SNNNDCMXZYWCCI-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-(4-Hydroxy-phenyl)benzofuran-5-OL |
| Canonical SMILES | Oc1ccc(-c2cc3cc(O)ccc3o2)cc1 |
| Clinical Status | Clinical Multi-Target |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.85 |
| Source | ChEMBL;BindingDB;TTD_MultiTarget |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB07032 |
|---|---|
| Drug Name | 2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL |
| CAS Number | nan |
| Groups | experimental |
| ATC Codes | nan |
| Description | nan |
Cross-references: BindingDB: 50152627 CHEMBL367588 ChemSpider: 571182 PDB: 397 PubChem:656936 PubChem:99443503 ZINC: ZINC000003816519
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P18505 | GABRB1 | Homo sapiens | Human | PF02931 PF02932 | 8.2 | pIC50 | TTD_MultiTarget |
| Q92731 | ESR2 | Homo sapiens | Human | PF12497 PF00104 PF00105 | 8.2 | IC50 | ChEMBL;BindingDB |
| P03372 | ESR1 | Homo sapiens | Human | PF12743 PF00104 PF02159 PF00105 | 6.8 | IC50 | ChEMBL;BindingDB |
| Q96WX4 | erg6 | Pneumocystis carinii (strain B80) | Pathogen | PF08241 PF08498 | 8.2 | pIC50 | TTD_MultiTarget |