Molecule Details
| InChIKey | SMYALUSCZJXWHG-UHFFFAOYSA-N |
|---|---|
| Compound Name | Altanserin |
| Canonical SMILES | O=C(c1ccc(F)cc1)C1CCN(CCn2c(=S)[nH]c3ccccc3c2=O)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.04 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB19972 |
|---|---|
| Drug Name | Altanserin |
| CAS Number | 76330-71-7 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Altanserin is a small molecule drug. The usage of the INN stem '-anserin' in the name indicates that Altanserin is a serotonin receptor antagonist. Altanserin is under investigation in clinical trial NCT03970239 (Serotonin in Impulse Control Disorders in Parkinson's Disease). Altanserin has a monois... |
Categories: Antidepressive Agents Central Nervous System Depressants Compounds used in a research, industrial, or household setting Contrast Media Diagnostic Uses of Chemicals Fluorine Radioisotopes Heterocyclic Compounds, Fused-Ring Neurotransmitter Agents Piperidines Quinazolines Quinazolinones Serotonin Agents Serotonin Receptor Antagonists
Cross-references: BindingDB: 50113332 ChEBI: 2613 CHEMBL62919 C11734 ZINC: ZINC000026174383
Target Activities (3)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P28223 | HTR2A | 5-hydroxytryptamine receptor 2A | inhibitor | targets |