Molecule Details
| InChIKey | SLPJGDQJLTYWCI-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole |
| Canonical SMILES | CN(C)c1nc2c(Br)c(Br)c(Br)c(Br)c2[nH]1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.05 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB04719 |
|---|---|
| Drug Name | DIMETHYL-(4,5,6,7-TETRABROMO-1H-BENZOIMIDAZOL-2-YL)-AMINE |
| CAS Number | nan |
| Groups | experimental |
| ATC Codes | nan |
| Description | nan |
Cross-references: BindingDB: 50156670 CHEMBL376505 ChemSpider: 4484252 PDB: K25 PubChem:5326976 PubChem:46505025 ZINC: ZINC000008830553
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P67870 | CSNK2B | Homo sapiens | Human | PF01214 | 7.4 | Ki | ChEMBL |
| Q8NEV1 | CSNK2A3 | Homo sapiens | Human | PF00069 | 7.4 | Ki | ChEMBL;BindingDB |
| P68400 | CSNK2A1 | Homo sapiens | Human | PF00069 | 7.0 | Ki | ChEMBL;BindingDB |
| P19784 | CSNK2A2 | Homo sapiens | Human | PF00069 | 7.0 | Ki | ChEMBL;BindingDB |
| P16083 | NQO2 | Homo sapiens | Human | PF02525 | 6.9 | IC50 | BindingDB |
| Q13627 | DYRK1A | Homo sapiens | Human | PF00069 | 6.7 | IC50 | ChEMBL;BindingDB |