Molecule Details
InChIKeySLKHMZQUNIHINK-WSVATBPTSA-N
Compound Name(5Z)-2-(1-adamantylimino)-5-[(3-methylbenzimidazol-5-yl)methylidene]imidazolidin-4-one
Canonical SMILESCn1cnc2ccc(/C=C3\N=C(NC45CC6CC(CC(C6)C4)C5)NC3=O)cc21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Cross-Family
Avg pChEMBL7.49
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
P49760 CLK2 Homo sapiens Human PF00069 8.5 IC50 ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 8.5 IC50 ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 8.2 IC50 ChEMBL
P49759 CLK1 Homo sapiens Human PF00069 8.1 IC50 ChEMBL
Q9Y463 DYRK1B Homo sapiens Human PF00069 8.0 IC50 ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 7.2 IC50 ChEMBL
Q9NR20 DYRK4 Homo sapiens Human PF00069 7.1 IC50 ChEMBL
Q92630 DYRK2 Homo sapiens Human PF00069 7.0 IC50 ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.2 IC50 ChEMBL
Q15078 CDK5R1 Homo sapiens Human PF03261 6.2 IC50 ChEMBL