Molecule Details
InChIKeySKOICOFQIQHEPE-UHFFFAOYSA-N
Compound NameCdk6/pim1-IN-1
Canonical SMILESCCN(CC)c1cnc2ccc(-c3nc(Nc4ccc(N5CCNCC5)cn4)ncc3F)cc2n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL7.03
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P11802 CDK4 Homo sapiens Human PF00069 8.4 IC50 ChEMBL;BindingDB
P24385 CCND1 Homo sapiens Human PF02984 PF00134 8.4 IC50 ChEMBL
Q00534 CDK6 Homo sapiens Human PF00069 7.4 IC50 ChEMBL;BindingDB
Q86V86 PIM3 Homo sapiens Human PF00069 7.0 IC50 ChEMBL;BindingDB
P50613 CDK7 Homo sapiens Human PF00069 6.4 IC50 ChEMBL
P51946 CCNH Homo sapiens Human PF16899 PF00134 6.4 IC50 ChEMBL;BindingDB
P51948 MNAT1 Homo sapiens Human PF25811 PF06391 PF17121 6.4 IC50 ChEMBL
O60563 CCNT1 Homo sapiens Human PF00134 PF21797 6.4 IC50 ChEMBL;BindingDB
P50750 CDK9 Homo sapiens Human PF00069 6.4 IC50 ChEMBL