Molecule Details
InChIKeySKMKJBYBPYBDMN-RYUDHWBXSA-N
Compound NameGdc-0134
Canonical SMILESNc1ncc(-c2cc(N3C[C@@H]4C[C@H]3CO4)nc(N3CCC(F)(F)C3)n2)cc1OC(F)F
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL8.1
SourceChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB17079
Drug NameGDC-0134
CAS Number1637394-01-4
Groups investigational
ATC Codes nan
Descriptionnan

Cross-references: CHEMBL3732012 ChemSpider: 58916542 ZINC: ZINC000220774924
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
Q12852 MAP3K12 Homo sapiens Human PF07714 8.5 IC50 ChEMBL
P80370 DLK1 Homo sapiens Human PF00008 8.0 IC50 ChEMBL
O43283 MAP3K13 Homo sapiens Human PF07714 7.8 IC50 ChEMBL