3-{4-[3-Amino-7-(trifluoromethoxy)-1,2-benzoxazol-4-yl]phenyl}-1-(2-fluoro-5-methylphenyl)urea

InChIKey	`SKANDNUVNSHDDS-UHFFFAOYSA-N`
Compound Name	3-{4-[3-Amino-7-(trifluoromethoxy)-1,2-benzoxazol-4-yl]phenyl}-1-(2-fluoro-5-methylphenyl)urea
Canonical SMILES	`Cc1ccc(F)c(NC(=O)Nc2ccc(-c3ccc(OC(F)(F)F)c4onc(N)c34)cc2)c1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	5
Pfam Stratification	Cross-Family
Avg pChEMBL	6.97
Source	BindingDB;ChEMBL;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P11511	CYP19A1	Homo sapiens	Human	PF00067	7.2	IC50	BindingDB
P36888	FLT3	Homo sapiens	Human	PF00047 PF07714	7.2	IC50	ChEMBL
Q02161	RHD	Homo sapiens	Human	PF00909	7.0	pIC50	TTD_MultiTarget
P35968	KDR	Homo sapiens	Human	PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854	6.8	IC50	ChEMBL;BindingDB
P10721	KIT	Homo sapiens	Human	PF00047 PF07714	6.5	IC50	ChEMBL;BindingDB