Molecule Details
InChIKeySJKCAVNLLOXGJL-UHFFFAOYSA-N
Compound Name6-[5-[3-[4-amino-3-(4-chlorophenyl)pyrazolo[3,4-d]pyrimidin-1-yl]phenyl]triazol-1-yl]-N-hydroxyhexanamide
Canonical SMILESNc1ncnc2c1c(-c1ccc(Cl)cc1)nn2-c1cccc(-c2cnnn2CCCCCC(=O)NO)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL7.45
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13547 HDAC1 Homo sapiens Human PF00850 9.6 Ki ChEMBL;BindingDB
Q9UBN7 HDAC6 Homo sapiens Human PF00850 PF02148 8.6 IC50 ChEMBL;BindingDB
O15379 HDAC3 Homo sapiens Human PF00850 7.7 IC50 ChEMBL;BindingDB
Q969S8 HDAC10 Homo sapiens Human PF00850 7.3 IC50 ChEMBL;BindingDB
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 6.9 Ki ChEMBL;BindingDB
Q96DB2 HDAC11 Homo sapiens Human PF00850 6.7 IC50 ChEMBL;BindingDB
Q92769 HDAC2 Homo sapiens Human PF00850 6.6 IC50 ChEMBL;BindingDB
P08631 HCK Homo sapiens Human PF07714 PF00017 PF00018 6.3 Ki ChEMBL;BindingDB