Molecule Details
InChIKeySJDGHXXYFFXVPE-UHFFFAOYSA-N
Compound Name2-(1-Methylindol-3-yl)-2-[5-(2-pyridin-4-ylethenyl)-3-pyridinyl]ethanamine
Canonical SMILESCn1cc(C(CN)c2cncc(C=Cc3ccncc3)c2)c2ccccc21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Homologous
Avg pChEMBL6.5
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13976 PRKG1 Homo sapiens Human PF00027 PF16808 PF00069 7.4 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 7.3 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.5 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.5 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.4 Ki ChEMBL
P31749 AKT1 Homo sapiens Human PF00169 PF00069 PF00433 6.2 Ki ChEMBL
Q13237 PRKG2 Homo sapiens Human PF00027 PF00069 6.1 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.1 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.0 Ki ChEMBL