Molecule Details
| InChIKey | SJDCIGRTECLEPF-UHFFFAOYSA-N |
|---|---|
| Compound Name | [2-[5-amino-1-(2-methyl-3H-benzimidazol-5-yl)pyrazole-4-carbonyl]-1H-indol-5-yl]-(4-piperidin-1-ylpiperidin-1-yl)methanone |
| Canonical SMILES | Cc1nc2cc(-n3ncc(C(=O)c4cc5cc(C(=O)N6CCC(N7CCCCC7)CC6)ccc5[nH]4)c3N)ccc2[nH]1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.39 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P21802 | FGFR2 | Homo sapiens | Human | PF07679 PF13927 PF07714 | 7.7 | IC50 | ChEMBL;BindingDB |
| P11362 | FGFR1 | Homo sapiens | Human | PF07679 PF00047 PF07714 | 7.4 | IC50 | ChEMBL;BindingDB |
| P22607 | FGFR3 | Homo sapiens | Human | PF21165 PF07679 PF13927 PF07714 | 7.1 | IC50 | ChEMBL;BindingDB |