2-N-[(4-chloro-1H-benzimidazol-5-yl)methyl]-4-N-[5-(1-methoxypropan-2-yl)-1H-pyrazol-3-yl]-2-N-methylpyrimidine-2,4-diamine

InChIKey	`SIXQNSLYMZXLPF-UHFFFAOYSA-N`
Compound Name	2-N-[(4-chloro-1H-benzimidazol-5-yl)methyl]-4-N-[5-(1-methoxypropan-2-yl)-1H-pyrazol-3-yl]-2-N-methylpyrimidine-2,4-diamine
Canonical SMILES	`COCC(C)c1cc(Nc2ccnc(N(C)Cc3ccc4[nH]cnc4c3Cl)n2)n[nH]1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.88
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q13153	PAK1	Homo sapiens	Human	PF00786 PF00069	7.5	Ki	ChEMBL;BindingDB
O14965	AURKA	Homo sapiens	Human	PF00069	6.9	Ki	ChEMBL;BindingDB
O96013	PAK4	Homo sapiens	Human	PF00786 PF00069	6.2	Ki	ChEMBL;BindingDB