Molecule Details
InChIKeySILHYVDKGHXGBL-UHFFFAOYSA-N
Compound NameGemilukast
Canonical SMILESCc1c(F)cccc1CCCCOc1ccc(C#Cc2ccc(F)c3c(CCCC(=O)O)c(C)n(CCCC(=O)O)c23)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL8.18
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB19882
Drug NameGemilukast
CAS Number1232861-58-3
Groups investigational
ATC Codes nan
DescriptionGemilukast is a small molecule drug. The usage of the INN stem '-lukast' in the name indicates that Gemilukast is a leukotriene receptor antagonist. Gemilukast is under investigation in clinical trial NCT01536041 (A Placebo and Active Controlled Study of ONO-6950 in Asthmatic Patients). Gemilukast h...

Categories: Acids, Acyclic Fatty Acids Fatty Acids, Volatile Heterocyclic Compounds, Fused-Ring Lipids
Cross-references: BindingDB: 50104921 CHEMBL3597634 ZINC: ZINC000114181311
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9Y271 CYSLTR1 Homo sapiens Human PF00001 8.8 IC50 ChEMBL;BindingDB
Q9NS75 CYSLTR2 Homo sapiens Human PF00001 7.6 IC50 ChEMBL;BindingDB