Molecule Details
InChIKeySIDIEQMDPONVCD-ZDUSSCGKSA-N
Compound Name(2S)-2-[[5-[3-(2-amino-4-oxo-3H-thieno[2,3-d]pyrimidin-6-yl)propyl]thiophene-3-carbonyl]amino]pentanedioic acid
Canonical SMILESNc1nc2sc(CCCc3cc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cs3)cc2c(=O)[nH]1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL8.4
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P14207 FOLR2 Homo sapiens Human PF03024 9.1 IC50 ChEMBL;BindingDB
P15328 FOLR1 Homo sapiens Human PF03024 9.0 IC50 ChEMBL;BindingDB
Q96NT5 SLC46A1 Homo sapiens Human PF07690 7.1 IC50 ChEMBL;BindingDB