1-fluoro-N-[4-[[[2-(oxan-4-ylamino)-8-propan-2-ylpyrazolo[1,5-a][1,3,5]triazin-4-yl]amino]methyl]phenyl]cyclopropane-1-carboxamide

InChIKey	`SICVBGDJQNMSDS-UHFFFAOYSA-N`
Compound Name	1-fluoro-N-[4-[[[2-(oxan-4-ylamino)-8-propan-2-ylpyrazolo[1,5-a][1,3,5]triazin-4-yl]amino]methyl]phenyl]cyclopropane-1-carboxamide
Canonical SMILES	`CC(C)c1cnn2c(NCc3ccc(NC(=O)C4(F)CC4)cc3)nc(NC3CCOCC3)nc12`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.74
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P50750	CDK9	Homo sapiens	Human	PF00069	7.5	IC50	ChEMBL
P50613	CDK7	Homo sapiens	Human	PF00069	6.6	IC50	ChEMBL
P24941	CDK2	Homo sapiens	Human	PF00069	6.1	IC50	ChEMBL