Molecule Details
InChIKeySHZPFCZPWGVEED-UHFFFAOYSA-N
Compound Name2-bromo-6-(4-methylphenyl)-5H-pyrrolo[2,3-b]pyrazine
Canonical SMILESCc1ccc(-c2cc3nc(Br)cnc3[nH]2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)5
Pfam Stratification Cross-Family
Avg pChEMBL6.82
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (5)
Target Gene Organism Category Pfam pChEMBL Type Source
Q00535 CDK5 Homo sapiens Human PF00069 8.1 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.0 Ki ChEMBL
P50613 CDK7 Homo sapiens Human PF00069 6.8 Ki ChEMBL
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 6.1 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.1 Ki ChEMBL