Molecule Details
InChIKeySHENEEFOURUIBP-UHFFFAOYSA-N
Compound NameN-[3-[[[2-(1H-indazol-5-ylamino)-3,4-dioxocyclobuten-1-yl]amino]methyl]phenyl]acetamide
Canonical SMILESCC(=O)Nc1cccc(CNc2c(Nc3ccc4[nH]ncc4c3)c(=O)c2=O)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)29
Pfam Stratification Cross-Family
Avg pChEMBL6.67
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (29)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13976 PRKG1 Homo sapiens Human PF00027 PF16808 PF00069 8.3 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 7.5 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 7.3 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 7.3 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 7.2 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 7.2 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.2 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 7.1 Ki ChEMBL
Q5VT25 CDC42BPA Homo sapiens Human PF00130 PF00780 PF08826 PF15796 PF25346 PF00069 PF00433 7.0 Ki ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 6.8 Ki ChEMBL
Q9HBY8 SGK2 Homo sapiens Human PF00069 PF00433 6.8 Ki ChEMBL
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 6.7 Ki ChEMBL
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.7 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q13237 PRKG2 Homo sapiens Human PF00027 PF00069 6.6 Ki ChEMBL
O60674 JAK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.4 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 6.4 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P28482 MAPK1 Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q8TDC3 BRSK1 Homo sapiens Human PF21122 PF00069 PF21115 6.2 Ki ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 6.1 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.1 Ki ChEMBL
P05129 PRKCG Homo sapiens Human PF00130 PF00168 PF00069 PF00433 6.1 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.1 Ki ChEMBL
O14757 CHEK1 Homo sapiens Human PF00069 6.0 Ki ChEMBL