6-chloro-4-[2-cyano-4-(trifluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)-2,3-dihydro-1,4-benzoxazine-7-sulfonamide

InChIKey	`SHCCRGIIPVJFHB-UHFFFAOYSA-N`
Compound Name	6-chloro-4-[2-cyano-4-(trifluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)-2,3-dihydro-1,4-benzoxazine-7-sulfonamide
Canonical SMILES	`N#Cc1cc(C(F)(F)F)ccc1N1CCOc2cc(S(=O)(=O)Nc3nccs3)c(Cl)cc21`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	6.61
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q15858	SCN9A	Homo sapiens	Human	PF00520 PF24609 PF06512 PF11933	7.0	IC50	ChEMBL;BindingDB
Q14524	SCN5A	Homo sapiens	Human	PF00520 PF24609 PF06512 PF11933	6.2	IC50	ChEMBL;BindingDB