InChIKey	SGEGOXDYSFKCPT-UHFFFAOYSA-N
Compound Name	Vilazodone
Canonical SMILES	N#Cc1ccc2[nH]cc(CCCCN3CCN(c4ccc5oc(C(N)=O)cc5c4)CC3)c2c1
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	18
Pfam Stratification	Cross-Family
Avg pChEMBL	6.89
Source	ChEMBL;BindingDB;TTD_MultiTarget

DrugBank ID	DB06684
Drug Name	Vilazodone
CAS Number	163521-12-8
Groups	approved investigational
ATC Codes	N06AX24
Description	Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. Vilazodone may also be associated with less sexual dysfunction and weight gain[A6947]. Vilazodone was given FDA approval on January 21, 201...

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Categories: Agents that produce hypertension Antidepressive Agents Antidepressive Agents Indicated for Depression Benzofurans Central Nervous System Agents Central Nervous System Depressants Cytochrome P-450 CYP2C19 Substrates Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (moderate) Cytochrome P-450 CYP2D6 Substrates Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Heterocyclic Compounds, Fused-Ring Indoles Membrane Transport Modulators Nervous System Neurotransmitter Agents Neurotransmitter Uptake Inhibitors Piperazines Psychoanaleptics Psychotropic Drugs Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome Serotonin 5-HT1 Receptor Agonists Serotonin Agents Serotonin Modulators Serotonin Receptor Agonists Serotonin antagonist and reuptake inhibitors (SARIs)

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Cross-references: BindingDB: 50151982 ChEBI: 70707 CHEMBL439849 ChemSpider: 5293518 Drugs Product Database (DPD): 22626 D09698 PDB: YG7 PubChem:6918314 PubChem:175427083 RxCUI: 1086769 Wikipedia: Vilazodone ZINC: ZINC000001542113