Molecule Details
| InChIKey | SFYSZVJXKDRKMX-UHFFFAOYSA-N |
|---|---|
| Compound Name | 5-[(cyclopentylamino)methyl]-N-(naphthalen-2-ylmethyl)-3-(4-pentylphenyl)sulfonyl-7-azabicyclo[2.2.1]heptan-2-amine |
| Canonical SMILES | CCCCCc1ccc(S(=O)(=O)C2C3NC(CC3CNC3CCCC3)C2NCc2ccc3ccccc3c2)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.47 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q17SB2 | Plasmodium falciparum | Pathogen | PF00026 | 8.0 | IC50 | ChEMBL | |
| Q8IM16 | PMIV | Plasmodium falciparum (isolate 3D7) | Pathogen | PF00026 | 8.0 | IC50 | BindingDB |
| P39898 | PMI | Plasmodium falciparum (isolate HB3) | Pathogen | PF00026 | 7.0 | IC50 | ChEMBL;BindingDB |
| P46925 | PMII | Plasmodium falciparum (isolate HB3) | Pathogen | PF00026 | 7.0 | IC50 | ChEMBL;BindingDB |