Molecule Details
InChIKeySFGWUTHNZVSATD-UHFFFAOYSA-N
Compound Name2-Aminothiazole 6
Canonical SMILESCC(C)(C)c1cnc(CSc2cnc(Nc3ccccc3)s2)o1
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)11
Pfam Stratification Cross-Family
Avg pChEMBL7.87
SourceChEMBL;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (11)
Target Gene Organism Category Pfam pChEMBL Type Source
O96020 CCNE2 Homo sapiens Human PF02984 PF00134 8.4 IC50 ChEMBL
P24864 CCNE1 Homo sapiens Human PF02984 PF00134 8.4 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 8.4 pIC50 TTD_MultiTarget
P06493 CDK1 Homo sapiens Human PF00069 8.2 pIC50 TTD_MultiTarget
P11802 CDK4 Homo sapiens Human PF00069 8.2 pIC50 TTD_MultiTarget
O95067 CCNB2 Homo sapiens Human PF02984 PF00134 7.9 IC50 ChEMBL
P14635 CCNB1 Homo sapiens Human PF02984 PF00134 7.9 IC50 ChEMBL
Q8WWL7 CCNB3 Homo sapiens Human PF02984 PF00134 7.9 IC50 ChEMBL
P24385 CCND1 Homo sapiens Human PF02984 PF00134 7.1 IC50 ChEMBL
P30279 CCND2 Homo sapiens Human PF02984 PF00134 7.1 IC50 ChEMBL
P30281 CCND3 Homo sapiens Human PF02984 PF00134 7.1 IC50 ChEMBL