20-Ethyl-17,23-dioxa-4,14,20,26-tetrazahexacyclo[24.6.1.17,14.02,6.08,13.027,32]tetratriaconta-1(33),2(6),7(34),8,10,12,27,29,31-nonaene-3,5-dione

InChIKey	`SFDFKLDQKSPRHB-UHFFFAOYSA-N`
Compound Name	20-Ethyl-17,23-dioxa-4,14,20,26-tetrazahexacyclo[24.6.1.17,14.02,6.08,13.027,32]tetratriaconta-1(33),2(6),7(34),8,10,12,27,29,31-nonaene-3,5-dione
Canonical SMILES	`CCN1CCOCCn2cc(c3ccccc32)C2=C(C(=O)NC2=O)c2cn(c3ccccc23)CCOCC1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	15
Pfam Stratification	Cross-Family
Avg pChEMBL	6.7
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P05771	PRKCB	Homo sapiens	Human	PF00130 PF00168 PF00069 PF00433	8.0	IC50	ChEMBL;BindingDB
P49841	GSK3B	Homo sapiens	Human	PF00069	7.7	IC50	ChEMBL;BindingDB
Q02156	PRKCE	Homo sapiens	Human	PF00130 PF00168 PF00069 PF00433	7.1	IC50	ChEMBL;BindingDB
P17252	PRKCA	Homo sapiens	Human	PF00130 PF00168 PF00069 PF00433	7.0	IC50	ChEMBL;BindingDB
P18505	GABRB1	Homo sapiens	Human	PF02931 PF02932	6.8	pIC50	TTD_MultiTarget
O95067	CCNB2	Homo sapiens	Human	PF02984 PF00134	6.6	IC50	ChEMBL
P06493	CDK1	Homo sapiens	Human	PF00069	6.6	pIC50	TTD_MultiTarget
P14635	CCNB1	Homo sapiens	Human	PF02984 PF00134	6.6	IC50	ChEMBL
Q8WWL7	CCNB3	Homo sapiens	Human	PF02984 PF00134	6.6	IC50	ChEMBL
P05129	PRKCG	Homo sapiens	Human	PF00130 PF00168 PF00069 PF00433	6.5	IC50	ChEMBL;BindingDB
Q05655	PRKCD	Homo sapiens	Human	PF00130 PF21494 PF00069 PF00433	6.5	IC50	ChEMBL;BindingDB
Q13554	CAMK2B	Homo sapiens	Human	PF08332 PF00069	6.1	IC50	ChEMBL
Q13555	CAMK2G	Homo sapiens	Human	PF08332 PF00069	6.1	IC50	ChEMBL
Q13557	CAMK2D	Homo sapiens	Human	PF08332 PF00069	6.1	IC50	ChEMBL;BindingDB
Q9UQM7	CAMK2A	Homo sapiens	Human	PF08332 PF00069	6.1	IC50	ChEMBL