InChIKey	SEEPANYCNGTZFQ-UHFFFAOYSA-N
Canonical SMILES	Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Cross-Family
Avg pChEMBL	6.68
Source	BindingDB;ChEMBL

DrugBank ID	DB00359
Drug Name	Sulfadiazine
CAS Number	68-35-9
Groups	approved investigational vet_approved
ATC Codes	J01EE06 J01EC02 G01AE10 J01EE02
Description	One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.

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Categories: Amides Amines Aniline Compounds Anti-Bacterial Agents Anti-Infective Agents Antibacterials for Systemic Use Antiinfectives for Systemic Use Antiparasitic Agents Antiprotozoals Benzene Derivatives Benzenesulfonamides Blood Glucose Lowering Agents Coccidiostats Cytochrome P-450 CYP2C8 Substrates Cytochrome P-450 CYP2C9 Inhibitors Cytochrome P-450 CYP2C9 Inhibitors (strength unknown) Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Drugs that are Mainly Renally Excreted Genito Urinary System and Sex Hormones Gynecological Antiinfectives and Antiseptics Hypoglycemia-Associated Agents Intermediate-Acting Antibacterial Sulfonamides Methemoglobinemia Associated Agents Sulfanilamides Sulfonamide Antibacterial Sulfonamides Sulfonamides and trimethoprim Sulfones Sulfur Compounds

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Cross-references: BindingDB: 50166571 ChEBI: 9328 CHEMBL439 ChemSpider: 5026 Drugs Product Database (DPD): 8199 C07658 D00587 PharmGKB: PA451539 PubChem:5215 PubChem:46506164 RxCUI: 10171 Therapeutic Targets Database: DAP001238 Wikipedia: Sulfadiazine ZINC: ZINC000000120319