Molecule Details
| InChIKey | SCQZRFDFSKEVKQ-JGVFFNPUSA-N |
|---|---|
| Compound Name | [(1S,5R)-3,6-diazabicyclo[3.2.1]octan-3-yl]-(5-fluorofuran-2-yl)methanone |
| Canonical SMILES | O=C(c1ccc(F)o1)N1C[C@@H]2CN[C@H](C2)C1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.18 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P17787 | CHRNB2 | Homo sapiens | Human | PF02931 PF02932 | 8.3 | Ki | ChEMBL |
| P43681 | CHRNA4 | Homo sapiens | Human | PF02931 PF02932 | 8.3 | Ki | ChEMBL;BindingDB |
| P30926 | CHRNB4 | Homo sapiens | Human | PF02931 PF02932 | 6.0 | Ki | ChEMBL |
| P32297 | CHRNA3 | Homo sapiens | Human | PF02931 PF02932 | 6.0 | Ki | ChEMBL |