N-(4-(3-(2-(2-(1-methylpyrrolidin-2-yl)ethylamino)pyrimidin-4-yl)pyridin-2-yloxy)naphthalen-1-yl)-1H-benzo[d]imidazol-2-amine

InChIKey	`SBSYQSASKXLENU-UHFFFAOYSA-N`
Compound Name	N-(4-(3-(2-(2-(1-methylpyrrolidin-2-yl)ethylamino)pyrimidin-4-yl)pyridin-2-yloxy)naphthalen-1-yl)-1H-benzo[d]imidazol-2-amine
Canonical SMILES	`CN1CCCC1CCNc1nccc(-c2cccnc2Oc2ccc(Nc3nc4ccccc4[nH]3)c3ccccc23)n1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	5
Pfam Stratification	Cross-Family
Avg pChEMBL	7.28
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q02763	TEK	Homo sapiens	Human	PF00041 PF10430 PF07714	8.7	IC50	ChEMBL;BindingDB
O75716	STK16	Homo sapiens	Human	PF00069	7.3	pIC50	TTD_MultiTarget
Q96GD4	AURKB	Homo sapiens	Human	PF00069	7.3	IC50	ChEMBL;BindingDB
P06239	LCK	Homo sapiens	Human	PF07714 PF00017 PF00018	6.6	IC50	ChEMBL;BindingDB
O14965	AURKA	Homo sapiens	Human	PF00069	6.5	IC50	ChEMBL;BindingDB