Molecule Details
| InChIKey | SBGMPUIVPOGTGN-UHFFFAOYSA-N |
|---|---|
| Compound Name | N1-(7-(4-(dimethylamino)phenyl)-1,6-naphthyridin-5-yl)butane-1,4-diamine |
| Canonical SMILES | CN(C)c1ccc(-c2cc3ncccc3c(NCCCCN)n2)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.95 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P43405 | SYK | Homo sapiens | Human | PF07714 PF00017 | 7.7 | IC50 | ChEMBL;BindingDB |
| Q15046 | KARS1 | Homo sapiens | Human | PF00152 PF01336 | 7.5 | IC50 | ChEMBL;BindingDB |
| P42681 | TXK | Homo sapiens | Human | PF07714 PF00017 PF00018 | 6.4 | Kd | ChEMBL;BindingDB |
| Q9H2G2 | SLK | Homo sapiens | Human | PF00069 PF12474 | 6.2 | Kd | ChEMBL;BindingDB |