Molecule Details
| InChIKey | SBGAHKXLTGCPRN-XMMPIXPASA-N |
|---|---|
| Compound Name | (2R)-N-[3-ethyl-5-(4-methylimidazol-1-yl)phenyl]-2-[methyl(pyrimidin-5-yl)amino]-2,3-dihydro-1H-indene-5-carboxamide |
| Canonical SMILES | CCc1cc(NC(=O)c2ccc3c(c2)C[C@H](N(C)c2cncnc2)C3)cc(-n2cnc(C)c2)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.75 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q08345 | DDR1 | Homo sapiens | Human | PF21114 PF00754 PF07714 | 7.8 | IC50 | ChEMBL;BindingDB |
| Q16288 | NTRK3 | Homo sapiens | Human | PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 | 6.4 | IC50 | ChEMBL;BindingDB |
| P04629 | NTRK1 | Homo sapiens | Human | PF13855 PF16920 PF07714 PF18613 | 6.4 | IC50 | ChEMBL;BindingDB |
| Q16832 | DDR2 | Homo sapiens | Human | PF21114 PF00754 PF07714 | 6.3 | IC50 | ChEMBL;BindingDB |