Molecule Details
InChIKeySBFPHSVZEXSHTL-UHFFFAOYSA-N
Compound NameN-[5-(1-benzyltriazol-4-yl)-1H-indazol-3-yl]-3-fluorobenzamide
Canonical SMILESO=C(Nc1n[nH]c2ccc(-c3cn(Cc4ccccc4)nn3)cc12)c1cccc(F)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)62
Pfam Stratification Cross-Family
Avg pChEMBL6.78
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (62)
Target Gene Organism Category Pfam pChEMBL Type Source
O00311 CDC7 Homo sapiens Human PF00069 9.2 Ki ChEMBL;BindingDB
P78368 CSNK1G2 Homo sapiens Human PF12605 PF00069 8.4 Ki ChEMBL
P68400 CSNK2A1 Homo sapiens Human PF00069 8.2 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 8.0 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 7.9 Ki ChEMBL
Q9HCP0 CSNK1G1 Homo sapiens Human PF12605 PF00069 7.9 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 7.8 Ki ChEMBL
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 7.7 Ki ChEMBL
Q9Y6M4 CSNK1G3 Homo sapiens Human PF12605 PF00069 7.7 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 7.5 Ki ChEMBL
Q9H2X6 HIPK2 Homo sapiens Human PF00069 7.5 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 7.3 Ki ChEMBL
P28482 MAPK1 Homo sapiens Human PF00069 7.1 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 7.1 Ki ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 7.0 Ki ChEMBL
P50613 CDK7 Homo sapiens Human PF00069 7.0 Ki ChEMBL
Q13131 PRKAA1 Homo sapiens Human PF16579 PF21147 PF00069 7.0 Ki ChEMBL
Q9HBY8 SGK2 Homo sapiens Human PF00069 PF00433 7.0 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 6.9 Ki ChEMBL
O15264 MAPK13 Homo sapiens Human PF00069 6.9 Ki ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 6.9 Ki ChEMBL
P50750 CDK9 Homo sapiens Human PF00069 6.9 Ki ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 6.8 Ki ChEMBL
Q06418 TYRO3 Homo sapiens Human PF00041 PF07679 PF07714 6.8 Ki ChEMBL
Q13976 PRKG1 Homo sapiens Human PF00027 PF16808 PF00069 6.8 Ki ChEMBL
O60674 JAK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.7 Ki ChEMBL
P27448 MARK3 Homo sapiens Human PF02149 PF00069 PF00627 6.7 Ki ChEMBL
P45984 MAPK9 Homo sapiens Human PF00069 6.7 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.7 Ki ChEMBL
P53778 MAPK12 Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 6.7 Ki ChEMBL
P48729 CSNK1A1 Homo sapiens Human PF00069 6.6 Ki ChEMBL
P51617 IRAK1 Homo sapiens Human PF00531 PF00069 6.6 Ki ChEMBL
Q9Y243 AKT3 Homo sapiens Human PF00169 PF00069 PF00433 6.6 Ki ChEMBL
O75582 RPS6KA5 Homo sapiens Human PF00069 PF00433 6.5 Ki ChEMBL
P05129 PRKCG Homo sapiens Human PF00130 PF00168 PF00069 PF00433 6.5 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.5 Ki ChEMBL
P49137 MAPKAPK2 Homo sapiens Human PF00069 6.5 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.5 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.5 Ki ChEMBL
P06241 FYN Homo sapiens Human PF07714 PF00017 PF00018 6.4 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.4 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.3 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.3 Ki ChEMBL
P42685 FRK Homo sapiens Human PF07714 PF00017 PF00018 6.3 Ki ChEMBL
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.3 Ki ChEMBL
Q13555 CAMK2G Homo sapiens Human PF08332 PF00069 6.3 Ki ChEMBL
Q13557 CAMK2D Homo sapiens Human PF08332 PF00069 6.3 Ki ChEMBL
Q8N4C8 MINK1 Homo sapiens Human PF00780 PF00069 6.3 Ki ChEMBL
Q8NE63 HIPK4 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q9BXA7 TSSK1B Homo sapiens Human PF00069 6.3 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.1 Ki ChEMBL
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 6.1 Ki ChEMBL
P16591 FER Homo sapiens Human PF00611 PF07714 PF00017 6.1 Ki ChEMBL
P45983 MAPK8 Homo sapiens Human PF00069 6.1 Ki ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 6.1 Ki ChEMBL
P51957 NEK4 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q86V86 PIM3 Homo sapiens Human PF00069 6.1 Ki ChEMBL
O96013 PAK4 Homo sapiens Human PF00786 PF00069 6.0 Ki ChEMBL
P22607 FGFR3 Homo sapiens Human PF21165 PF07679 PF13927 PF07714 6.0 Ki ChEMBL
Q13237 PRKG2 Homo sapiens Human PF00027 PF00069 6.0 Ki ChEMBL
Q96SB4 SRPK1 Homo sapiens Human PF00069 6.0 Ki ChEMBL