4-(4-(4-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidin-1-yl)phenylsulfonyl)-N-hydroxytetrahydro-2H-pyran-4-carboxamide

InChIKey	`SAXMIJMROZDLCS-UHFFFAOYSA-N`
Compound Name	4-(4-(4-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidin-1-yl)phenylsulfonyl)-N-hydroxytetrahydro-2H-pyran-4-carboxamide
Canonical SMILES	`COc1cc2c(cc1OC)CN(C(=O)C1CCN(c3ccc(S(=O)(=O)C4(C(=O)NO)CCOCC4)cc3)CC1)CC2`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	8.21
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P08253	MMP2	Homo sapiens	Human	PF00040 PF00045 PF00413	8.2	pIC50	TTD_MultiTarget
P45452	MMP13	Homo sapiens	Human	PF00045 PF00413 PF01471	8.2	IC50	ChEMBL;BindingDB
P18843	nadE	Escherichia coli (strain K12)	Pathogen	PF02540	8.2	pIC50	TTD_MultiTarget