Molecule Details
| InChIKey | RZXMIHOUHYSGJO-UHFFFAOYSA-N |
|---|---|
| Compound Name | Gne-2861 |
| Canonical SMILES | COCCNc1nc2ccc(C#CC3(O)CCCCC3)cc2n1-c1ccnc(N)n1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.19 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O96013 | PAK4 | Homo sapiens | Human | PF00786 PF00069 | 8.4 | IC50 | ChEMBL;BindingDB |
| Q9NQU5 | PAK6 | Homo sapiens | Human | PF00786 PF00069 | 7.4 | IC50 | ChEMBL;BindingDB |
| Q9P286 | PAK5 | Homo sapiens | Human | PF00786 PF00069 | 6.9 | IC50 | ChEMBL;BindingDB |
| Q13177 | PAK2 | Homo sapiens | Human | PF00786 PF00069 | 6.0 | IC50 | ChEMBL;BindingDB |