InChIKey	RXWNCPJZOCPEPQ-NVWDDTSBSA-N
Compound Name	Puromycin
Canonical SMILES	COc1ccc(C[C@H](N)C(=O)N[C@H]2[C@@H](O)[C@H](n3cnc4c(N(C)C)ncnc43)O[C@@H]2CO)cc1
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	55
Pfam Stratification	Cross-Family
Avg pChEMBL	6.05
Source	ChEMBL

DrugBank ID	DB08437
Drug Name	Puromycin
CAS Number	53-79-2
Groups	experimental
ATC Codes	nan
Description	Puromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting in significant cell death at appropriate doses.

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Categories: Acids, Carbocyclic Agents that produce neuromuscular block (indirect) Aminoglycoside Antibacterials Anti-Bacterial Agents Anti-Infective Agents Antimetabolites Antineoplastic Agents Antiparasitic Agents Antiprotozoals Carbohydrates Cinnamates Enzyme Inhibitors Glycosides Heterocyclic Compounds, Fused-Ring Nephrotoxic agents Noxae Nucleic Acids, Nucleotides, and Nucleosides Nucleosides Protein Synthesis Inhibitors Purine Nucleosides Purines Toxic Actions Trypanocidal Agents

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Cross-references: BindingDB: 50277158 ChEBI: 17939 CHEMBL469912 ChemSpider: 388623 C01610 PDB: PUY PubChem:439530 PubChem:99444908 Wikipedia: Puromycin ZINC: ZINC000053147179