Molecule Details
InChIKeyRXVOXSGTUROJOL-UHFFFAOYSA-N
Compound Name2-Chloro-11-oxo-10,11-dihydro-5H-3,4,5,10-tetraaza-dibenzo[a,d]cycloheptene-6-carboxylic acid amide
Canonical SMILESNC(=O)c1cccc2c1Nc1nnc(Cl)cc1C(=O)N2
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)11
Pfam Stratification Cross-Family
Avg pChEMBL6.4
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (11)
Target Gene Organism Category Pfam pChEMBL Type Source
P49840 GSK3A Homo sapiens Human PF00069 7.6 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 7.0 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 6.5 Ki ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 6.4 Ki ChEMBL
P17948 FLT1 Homo sapiens Human PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.4 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.2 Ki ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 6.2 Ki ChEMBL
P04629 NTRK1 Homo sapiens Human PF13855 PF16920 PF07714 PF18613 6.1 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.0 Ki ChEMBL