Molecule Details
| InChIKey | RXIUGRLQOGTTNP-UHFFFAOYSA-N |
|---|---|
| Compound Name | 6-[[4-(6-fluoro-1H-indol-3-yl)piperidin-1-yl]methyl]-2-methyl-6,7-dihydro-5H-1,3-benzoxazol-4-one |
| Canonical SMILES | Cc1nc2c(o1)CC(CN1CCC(c3c[nH]c4cc(F)ccc34)CC1)CC2=O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.08 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P28223 | HTR2A | Homo sapiens | Human | PF00001 | 8.3 | Ki | ChEMBL |
| P21728 | DRD1 | Homo sapiens | Human | PF00001 | 7.5 | Ki | ChEMBL |
| P28335 | HTR2C | Homo sapiens | Human | PF00001 | 7.0 | Ki | ChEMBL |
| P14416 | DRD2 | Homo sapiens | Human | PF00001 | 6.7 | Ki | ChEMBL |
| P50406 | HTR6 | Homo sapiens | Human | PF00001 | 6.7 | Ki | ChEMBL |
| P08908 | HTR1A | Homo sapiens | Human | PF00001 | 6.3 | Ki | ChEMBL |