N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(diethylamino)but-2-ynamide

InChIKey	`RWRYVPUMPZVZSS-UHFFFAOYSA-N`
Compound Name	N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(diethylamino)but-2-ynamide
Canonical SMILES	`CCN(CC)CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.92
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P00533	EGFR	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	7.9	IC50	ChEMBL;BindingDB
P04626	ERBB2	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	7.9	pIC50	TTD_MultiTarget