RTGPQVHYQAWJEV-OYRHEFFESA-N

InChIKey	`RTGPQVHYQAWJEV-OYRHEFFESA-N`
Canonical SMILES	`CN1CCN([C@H]2C[C@@H](c3nc(-c4ccc5ccc(-c6ccccc6)nc5c4F)c4c(N)ncnn43)C2)CC1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.51
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P08069	IGF1R	Homo sapiens	Human	PF00757 PF07714 PF01030	7.8	IC50	ChEMBL;BindingDB
P06213	INSR	Homo sapiens	Human	PF00757 PF17870 PF07714 PF01030	7.2	IC50	ChEMBL;BindingDB