4-(2,5-dioxopyrrolidin-1-yl)-N-[(2R)-1-[[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]amino]-3-methylsulfanyl-1-oxopropan-2-yl]-2-sulfanylbutanamide

InChIKey	`RSWUWSKXIDLCIR-PYNWJHIZSA-N`
Compound Name	4-(2,5-dioxopyrrolidin-1-yl)-N-[(2R)-1-[[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]amino]-3-methylsulfanyl-1-oxopropan-2-yl]-2-sulfanylbutanamide
Canonical SMILES	`CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CSC)NC(=O)C(S)CCN1C(=O)CCC1=O`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	4
Pfam Stratification	Cross-Family
Avg pChEMBL	7.68
Source	ChEMBL;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P14780	MMP9	Homo sapiens	Human	PF00040 PF00045 PF00413	8.1	IC50	ChEMBL
P22894	MMP8	Homo sapiens	Human	PF00045 PF00413 PF01471	8.0	IC50	ChEMBL
P08254	MMP3	Homo sapiens	Human	PF00045 PF00413 PF01471	7.1	IC50	ChEMBL
P18843	nadE	Escherichia coli (strain K12)	Pathogen	PF02540	7.6	pIC50	TTD_MultiTarget