5-[2-[3-(1,4-diazabicyclo[3.2.2]nonan-4-yl)anilino]-5-methylpyrimidin-4-yl]-N,4-dimethyl-1,3-thiazol-2-amine

InChIKey	`RSTOVEUALSXORR-UHFFFAOYSA-N`
Compound Name	5-[2-[3-(1,4-diazabicyclo[3.2.2]nonan-4-yl)anilino]-5-methylpyrimidin-4-yl]-N,4-dimethyl-1,3-thiazol-2-amine
Canonical SMILES	`CNc1nc(C)c(-c2nc(Nc3cccc(N4CCN5CCC4CC5)c3)ncc2C)s1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	4
Pfam Stratification	Cross-Family
Avg pChEMBL	7.13
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O60563	CCNT1	Homo sapiens	Human	PF00134 PF21797	8.0	Ki	ChEMBL
P50750	CDK9	Homo sapiens	Human	PF00069	8.0	Ki	ChEMBL
P50613	CDK7	Homo sapiens	Human	PF00069	6.3	Ki	ChEMBL
P51946	CCNH	Homo sapiens	Human	PF16899 PF00134	6.3	Ki	ChEMBL