Molecule Details
InChIKeyRSAGFYGPXOAVNX-RUZDIDTESA-N
Compound Name(2R)-2-[[5-[2-(4-butylphenyl)ethynyl]thiophen-2-yl]sulfonylamino]-N-hydroxy-3-(1H-indol-3-yl)propanamide
Canonical SMILESCCCCc1ccc(C#Cc2ccc(S(=O)(=O)N[C@H](Cc3c[nH]c4ccccc34)C(=O)NO)s2)cc1
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL7.17
SourceChEMBL;BindingDB;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
P08253 MMP2 Homo sapiens Human PF00040 PF00045 PF00413 8.2 pIC50 TTD_MultiTarget
Q9NPA2 MMP25 Homo sapiens Human PF00045 PF00413 PF01471 7.1 IC50 ChEMBL;BindingDB
P14780 MMP9 Homo sapiens Human PF00040 PF00045 PF00413 7.1 IC50 ChEMBL;BindingDB
Q9ULZ9 MMP17 Homo sapiens Human PF00045 PF00413 PF01471 7.1 pIC50 TTD_MultiTarget
P08254 MMP3 Homo sapiens Human PF00045 PF00413 PF01471 7.0 IC50 ChEMBL;BindingDB
P22894 MMP8 Homo sapiens Human PF00045 PF00413 PF01471 6.5 IC50 ChEMBL;BindingDB
P18843 nadE Escherichia coli (strain K12) Pathogen PF02540 7.1 pIC50 TTD_MultiTarget