Molecule Details
| InChIKey | RREMAKLSNSMREF-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-hydroxy-5-(1-phenyl-3,4-dihydro-1H-isoquinolin-2-yl)pentanamide |
| Canonical SMILES | O=C(CCCCN1CCc2ccccc2C1c1ccccc1)NO |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.41 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9BY41 | HDAC8 | Homo sapiens | Human | PF00850 | 7.4 | IC50 | ChEMBL;BindingDB |
| Q13547 | HDAC1 | Homo sapiens | Human | PF00850 | 6.1 | IC50 | ChEMBL;BindingDB |
| O15379 | HDAC3 | Homo sapiens | Human | PF00850 | 6.1 | IC50 | ChEMBL;BindingDB |
| Q9Y618 | NCOR2 | Homo sapiens | Human | PF15784 PF00249 | 6.1 | IC50 | ChEMBL |