N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(5-((dimethylamino)methyl)furan-2-yl)thieno[3,2-d]pyrimidin-4-amine

InChIKey	`RRBYOZUVIOQSSM-UHFFFAOYSA-N`
Compound Name	N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(5-((dimethylamino)methyl)furan-2-yl)thieno[3,2-d]pyrimidin-4-amine
Canonical SMILES	`CN(C)Cc1ccc(-c2cc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3s2)o1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	8.7
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P00533	EGFR	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	8.7	IC50	ChEMBL;BindingDB
P04626	ERBB2	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	8.7	pIC50	TTD_MultiTarget