Molecule Details
InChIKeyRQVKVJIRFKVPBF-UHFFFAOYSA-N
Compound Name2-[(2-Amino-3-phenylpropyl)amino]-3-methyl-5-naphthalen-2-yl-6-pyridin-4-ylpyrimidin-4-one
Canonical SMILESCn1c(NCC(N)Cc2ccccc2)nc(-c2ccncc2)c(-c2ccc3ccccc3c2)c1=O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)13
Pfam Stratification Cross-Family
Avg pChEMBL7.01
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (13)
Target Gene Organism Category Pfam pChEMBL Type Source
Q16539 MAPK14 Homo sapiens Human PF00069 9.6 Ki ChEMBL
P53779 MAPK10 Homo sapiens Human PF00069 8.2 Ki ChEMBL
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 8.2 Ki ChEMBL
P45984 MAPK9 Homo sapiens Human PF00069 7.1 Ki ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 7.0 Ki ChEMBL
Q9H2G2 SLK Homo sapiens Human PF00069 PF12474 6.8 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.7 Ki ChEMBL
P07948 LYN Homo sapiens Human PF07714 PF00017 PF00018 6.5 Ki ChEMBL
P45983 MAPK8 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q15303 ERBB4 Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 6.3 Ki ChEMBL
P00533 EGFR Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 6.2 Ki ChEMBL
Q8N4C8 MINK1 Homo sapiens Human PF00780 PF00069 6.2 Ki ChEMBL
P41743 PRKCI Homo sapiens Human PF00130 PF00564 PF00069 PF00433 6.0 Ki ChEMBL