Molecule Details
| InChIKey | RPZIXRBMHRKWST-IBGZPJMESA-N |
|---|---|
| Compound Name | N-[5-[7-[(2S)-1-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]propan-2-yl]oxy-1,3-dihydro-2-benzofuran-5-yl]-2-methoxy-3-pyridinyl]-2-methoxyethanesulfonamide |
| Canonical SMILES | COCCS(=O)(=O)Nc1cc(-c2cc3c(c(O[C@@H](C)CN4CCC(C(C)(C)O)CC4)c2)COC3)cnc1OC |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.4 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q8NEB9 | PIK3C3 | Homo sapiens | Human | PF00454 PF00792 PF00613 | 7.6 | IC50 | ChEMBL;BindingDB |
| O00329 | PIK3CD | Homo sapiens | Human | PF00454 PF00792 PF02192 PF00794 PF00613 | 7.3 | IC50 | ChEMBL;BindingDB |
| P27986 | PIK3R1 | Homo sapiens | Human | PF16454 PF00620 PF00017 | 7.3 | IC50 | ChEMBL;BindingDB |